Research Index entry · Study
Calcium alpha-ketoglutarate restored memory connections in mice
- Evidence
- Mice
- Source
- doi.org
- Added
- 21 October 2026
What it is
Calcium alpha-ketoglutarate (CaAKG) is a molecule the body makes naturally and has been studied for healthy aging. In Alzheimer’s-model mice it restored synaptic plasticity, the strengthening of connections that memory depends on, and associative memory.
Where it stands
- Lab discovery
- Animal studies
- First studies in people
- Large trials
- Approved
Mouse and brain-slice work. No Alzheimer’s trial in people.
Update timeline
What changed
Newest first. Only changes to the subject itself appear here: new information, or something proven wrong.
- WatchingThe Scouts look again every Friday
Only new information or a correction shows up here, not another mention of the same thing.
- No changes yet
Nothing new or corrected since this entry was added.
Research connections
Why these belong together
A connection has to say what it adds. Shared keywords alone don’t count.
Practice · Journals
Microdose lithium orotate moves from Nature into caregiver threadsBoth are substances the body already has, and both restored memory in Alzheimer’s-model mice. Neither has been tested against Alzheimer’s in people yet.
Mice · trial registered