Alzheimer’s for Amateurs

January 2026 edition

The brain’s cleanup crew is becoming the story.

Read it on Substack
Inside a neuron with Alzheimer’s: abnormal tau, in blue, spreading through the cell.
National Institute on Aging, NIH · public domain

What’s inside

Feature

Why the neuron next door survives

Why one neuron copes with tau while its neighbour doesn’t: a lab search for the cell’s own disposal system.

Feature

The brain may be running short of lithium

A trace metal most people know as a psychiatric drug, and what mice suggest about it.

The roundup

Repairs, so far in mice

Three ways researchers restored memory or cleared damage in mice. None has reached people with Alzheimer’s.

The roundup

Risk, measured in people

Four studies of who develops dementia, and how much more often.

The roundup

Who’s protected, how we’ll test, who pays

Genes behind super agers, a finger-prick blood test, and this year’s research funding.

Spotted in the Wild

Worth a listen, worth a watch

A podcast and two short videos worth your time.